Weaving back and forth between two different times, locations and stages of a relationship, The Doctor's Daughter tells a fresh and unconventional love story that avoids clichés or preconceptions. In Trinidad in 1991, friends Nikki and Regan act on a passionate impulse that is both reckless - Regan is engaged to Howard at the time - and meaningful. Six years later, Regan and Nikki are lovers living together in Toronto. Nikki works in her father's doctor's office and maintains a close and deeply involved bond with her extended family. Yet she finds she is never able to truly be herself around the people who have known her all her life.

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