Nina Eberlin comes home to visit her now-divorced parents and while looking through a collection of pictures taken by her father and herself, she reflects on how the pictures illustrate the nature of families. She begins to tell the story of how her parents discovered their son Randall was autistic and how each reacted to that. Her mother had three more kids, all daughters, "the perfect children." The controversy over that and Randall's treatment pulls the parents apart. It also forces Nina and her older brother Mack to re-evaluate their relationship with each other and each parent.

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