Night of Champions (2010) was a PPV that took place on September 19, 2010 at the Allstate Arena in Chicago, Illinois. It was the fourth annual event under the "Night of Champions" name and the tenth annual event under the Vengeance/Night of Champions chronology. Similar to the previous three events, the concept of the show was that every championship in the company was defended at the event. Randy Orton, Sheamus, Wade Barrett, Edge, John Cena, and Chris Jericho competed in a Six-pack challenge elimination match for the WWE Championship. The Undertaker challenged Kane in a No Holds Barred match for the World Heavyweight Championship, Daniel Bryan faced The Miz for the US Championship, Dolph Ziggler faced Kofi Kingston for the IC Championship, A Tag Team Turmoil match took place for the Tag Team Belts, and The Big Show fought CM Punk in the first non title match at a Night of Champions PPV.

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