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The Substance

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Calorie Rating: 198
Released: 2024-09-07
MPAA Rating: R
Running Time: 141 Minutes
Budget: 17500000
Revenue 76506196
Homepage: https://mubi.com/en/thesubstance
Studios: Working Title Films, Blacksmith, Working Title Films,


A fading celebrity decides to use a black market drug, a cell-replicating substance that temporarily creates a younger, better version of herself.

Director / Directors

Anne Juin
Third Assistant Director
Matthieu de la Mortière
First Assistant Director

Clément Audebrand
Third Assistant Director
Benoit Seiller
Second Assistant Director
Mateo Cejoco
Third Assistant Director

Louis Tellier
Third Assistant Director
Marianne Huet
Script Supervisor


Cast

Demi Moore
Character: Elisabeth
Margaret Qualley
Character: Sue
Dennis Quaid
Character: Harvey

Edward Hamilton-Clark
Character: Fred
Gore Abrams
Character: Oliver
Oscar Lesage
Character: Troy

Christian Erickson
Character: Man at Diner
Robin Greer
Character: Male Nurse
Tom Morton
Character: Doctor

Hugo Diego Garcia
Character: Diego - Boyfriend
Daniel Knight
Character: Casting Director
Jonathon Carley
Character: Assistant Casting Director

Jiselle Henderkott
Character: Girl Auditioning / New Year's Eve Show Dancer
Akil Wingate
Character: TV Host
Vincent Colombe
Character: Man in Suit #1 - Harvey's Office

Billy Bentley
Character: Man in Suit #2
Lennard Ridsdale
Character: Man in Suit #3
Jordan Ford Silver
Character: Assistant Director - Pump It Up Show

Oscar Salem
Character: 2nd Assistant Director - Pump It Up Show
Viviane Bossina
Character: Sue's Assistant
Matthew Luret
Character: Floor Runner

Jana Bittnerová
Character: Maria
Olivier Raynal
Character: Alan - 2nd Agent
Tiffany Hofstetter
Character: Stylist

Nicolas Royer
Character: Guy in the Elevator
Nathan Rippy
Character: Assistant Director - New Year's Eve Show
Manon Arizmendi
Character: Little Girl - New Year's Eve Show

Virginie Kotlinski
Character: Mother - New Year's Eve Show
Brett Gillen
Character: Director of Photography - New Year's Eve Show
Charlotte Marquardt
Character: Screaming Woman

Léa Hengl
Character: Screaming Woman
Gaëlle Raymond
Character: Screaming Woman
Claire Lemaire
Character: Screaming Woman

Lila Boughoufala
Character: Screaming Woman
Aurélien Lorgnier
Character: Screaming Man
Ivan Sellier
Character: Screaming Man

Philip Schurer
Character: Screaming Man
Christian Bourmier
Character: Shareholder
Martin Graham
Character: Shareholder

Christian Bordeleau
Character: Shareholder
Patrick Hamel
Character: Shareholder
Didier Dhondt
Character: Shareholder

Jacques-Yves Dorges
Character: Shareholder
Jean-Claude Matthey
Character: Shareholder
Olivier Jarcin
Character: Shareholder

Jean-Luc Magneron
Character: Shareholder
Charlotte Murray
Character: Allison - Diner Waitress
Aaron Kahn
Character: Greeting Person

Gabriela Arnon
Character: Greeting Person
Nancy Josephson Lahoussine
Character: Greeting Person
Andrew Eldridge
Character: Greeting Person

Denise Powers
Character: Greeting Person
Bryan Jones
Character: Greeting Person
Adam Carage
Character: Happy Birthday Person

Maria McClurg
Character: Happy Birthday Person
Andrew Desmond
Character: Happy Birthday Person
Rebecca Lafont
Character: Happy Birthday Person

Laura Puech
Character: Isabella
Ryan Chidester
Character: Stagehand
Céline Vogt
Character: Elisabeth (Young) - Walk of Fame

Yannick Guérin
Character: Clumsy Burger Guy - Walk of Fame
Jean Miel
Character: Worker Walk of Fame
Paul Descoings
Character: Worker Walk of Fame

Benoit Lévêque
Character: Worker Walk of Fame
Arthur Molinet
Character: Cocktail Bartender
Manon Sachot
Character: Cocktail Lounge Couple

Bastien Jorelle
Character: Cocktail Lounge Couple
Kelly Hoarau
Character: Female Assistant - Towel
Michel Juskiewicz
Character: George - Harvey's Friend

Louise Greggory
Character: Restaurant Waitress
Christophe Sartirano
Character: Guy Looking at Sue
Florent Torres
Character: Guy Looking at Sue

Romain Caldeira
Character: Billboard Technician
Barthelemy Thomas
Character: Billboard Technician
Axel Baille
Character: Photographer

Ashley Lambert
Character: Additional Voices (voice)
Ranjani Brow
Character: Additional Voices (voice)
Chase Fein
Character: Additional Voices (voice)

Shane Sweet
Character: Additional Voices (voice)
William Calvert
Character: Additional Voices (voice)
Michael Corbett
Character: Additional Voices (voice)

Stephen Apostolina
Character: Additional Voices (voice)
Yann Bean
Character: The Substance (voice)
Audjyan Alcide
Character: Pump It Up Show Dancer

Jonathan Jenvrin
Character: Pump It Up Show Dancer
Mimi Maury
Character: Pump It Up Show Dancer
Amelye Solange
Character: Pump It Up Show Dancer

Kévin Table
Character: Pump It Up Show Dancer
Laura Boera
Character: Sparkle Your Life Show Dancer
Cissy Duc
Character: Sparkle Your Life Show Dancer

Sophie Mercier
Character: Sparkle Your Life Show Dancer
Marie Valton
Character: Sparkle Your Life Show Dancer
Katrina Budzynski
Character: New Year's Eve Show Dancer

Alicia Maury
Character: New Year's Eve Show Dancer
Megane Adamik
Character: New Year's Eve Show Dancer
Annalisa Pagnotta
Character: New Year's Eve Show Dancer

Maelle Dantigny
Character: New Year's Eve Show Dancer
Aleksandra Fontaine Kedzierska
Character: New Year's Eve Show Dancer
Pauline Sagetat
Character: New Year's Eve Show Dancer

Agustina Fitzsimons
Character: New Year's Eve Show Dancer
Elena Shcheglova
Character: New Year's Eve Show Dancer
Eve Marchant
Character: New Year's Eve Show Dancer

Lola Donati
Character: New Year's Eve Show Dancer
Kate Matthews
Character: New Year's Eve Show Dancer
Ophélie Jonard
Character: New Year's Eve Show Dancer

Pauline Richard
Character: New Year's Eve Show Dancer
Laureen Cappelliez
Character: New Year's Eve Show Dancer
Daria Panchenko
Character: New Year's Eve Show Dancer

Delphine Beaulieu
Character: New Year's Eve Show Dancer
Victoria Brun
Character: New Year's Eve Show Dancer
Cara Chapman
Character: New Year's Eve Show Dancer

Katharine Matthews
Character: New Year's Eve Show Dancer
Alexandra Faget
Character: New Year's Eve Show Dancer
Clémence Juville
Character: New Year's Eve Show Dancer

Margot L'Entete
Character: New Year's Eve Show Dancer
Hillary Sukhonos
Character: New Year's Eve Show Dancer
Matthew Géczy
Character: Bob Haswell (uncredited)

Namory Bakayoko
Character: Silhouette (uncredited)
Gregory Defleur
Character: Happy Birthday Person (uncredited)
Coralie Fargeat
Character: (uncredited)


Production and Crew

Erik Baiers
Executive Producer
Stanislas Reydellet
Production Design
Jérôme Gaspard
Stunt Coordinator

Sebastian Lochmann
Concept Artist
Richard Martin
Prosthetics Sculptor
Frédérique Arguello
Hair Department Head

Benjamin Kračun
Director of Photography
Marie Bouvet
Stunt Double
Frédéric Balmer
Special Effects Makeup Artist

Andrea Leanza
Prosthetics Sculptor
Krystell Morantin
Assistant Art Director
Denise Boccacci
Prosthetic Makeup Artist

Bryan Jones
Visual Effects Supervisor
Cécilia Blom
Set Decoration

Joffrey Darel
Stunt Driver
Catherine Georges
Camera Operator

Camille Damag
Costume Supervisor
Fabienne Menguy
Costume Supervisor

Steve de Rocco
Camera Operator


Chloè Acher
Second Assistant Camera
Yann Festinger
Video Assist Operator
Noémie Lance
Location Manager

Laure Caniaux
First Assistant Camera
Nahi Margot
Electrician

Olivier Maurin
Electrician
Nadege Marti
Location Scout

Benjamin Colleye
Additional First Assistant Camera
Tanguy Goasguen
Additional Grip
Gustin Guillaume
First Assistant Camera

Baptiste Herment
Production Accountant
Olivier Sargatal
Best Boy Electric

Vianne Burquier
Camera Intern
Marie-Sophie Daniel
First Assistant Camera
Jonas Poignant
Third Assistant Camera

Baptiste Marnière
Digital Imaging Technician

Stella Libert
First Assistant Camera
Benjamin Durfort
Assistant Editor

Thomas Gros
Key Grip

Katia Sourzac
Location Production Assistant
Charles Droudun
Electrician
Ludovic Tobaldi
Steadicam Operator

Christine Tamalet
Still Photographer
Tim Bevan
Producer

Alexandra Loewy
Executive Producer
Nicolas Royer
Executive Producer

Raffertie
Original Music Composer
Marison De
Special Effects Makeup Artist
Olivier Afonso
Special Effects Makeup Artist

Jean-Marc Benois
Key Hair Stylist
Sandrine Denis
Special Effects Makeup Artist
Oriane Cattiaux
Makeup Artist

Benjamin Celliez
Unit Production Manager
Julia Besnier
Production Accountant
Pierre-Yves Frohard
Production Coordinator

Abraham Goldblat
Post Production Supervisor

Dave Elsey
Prosthetic Supervisor
Lou Elsey
Prosthetic Supervisor
Louis Celnik
Carpenter

Marilyne Scarselli
Hair Supervisor
Marion Didier
Assistant Art Director
Cynthia Scigliuto
Makeup Artist

Honorine Sutter
Assistant Production Manager
Stéphanie Guillon
Key Makeup Artist

Bryony Rumble
Special Effects Makeup Artist
Mélissa Jacob
Additional Hairstylist
Lucky Nguyen
Makeup Artist

Tiva Nagchin
Post Production Supervisor
Brian Kinney
Special Effects Makeup Artist

Amélie Meseguer
Assistant Set Decoration
Jean Miel
Special Effects Supervisor
Guillaume Le Gouez
Visual Effects Supervisor

Guillaume Billy
Camera Trainee
Raphaëlle Beck
Extras Casting
Elsa Manunta
Set Costumer

Guillaume Baurez
Music Supervisor
Chloé Zobel
Property Master
Jacob Rogers
Digital Compositor

Jimmy Zhao
First Assistant Editor
Marjane Texier
Graphic Designer

Elsa Rolland
Assistant Property Master
Christophe Arnaud
Additional Second Assistant Camera
Steve Sebir
Assistant Location Manager

Louis Auger
Digital Compositor
Thomas Burgess
Steadicam Operator
Olaf Taittinger
Special Effects

Téo L'Huillier
Digital Compositor
Louis Lion
Digital Compositor
Christophe Riso
Assistant Location Manager

Isalys Gillet
Location Assistant
Aurélie Boutet
Casting Assistant

Pierre Olivier Persin
Makeup Effects Designer
Stéphane Bécimol
Art Direction

Emmanuelle Youchnovski
Costume Designer
Valérie Deloof
Sound Designer

Olga Pasternak
Supervising Dialogue Editor
Thomas Pichon
Dialogue Editor

Margaux Peyre
Boom Operator
Grégory Vincent
Foley Artist

Stéphane Thiébaut
Sound Re-Recording Mixer
Victor Fleurant
Sound Editor
Judah Getz
ADR Mixer

Victor Praud
Sound Re-Recording Mixer

Valérie Deloof
Sound Editor
Claire Bernengo
Boom Operator
Lucien Richardson
Supervising Dialogue Editor

Amélie Meseguer
Art Direction

Arnaud Denis
Art Direction
Gladys Garot
Art Direction
Julie Plumelle
Art Direction

Nathalie Vaïsse
Art Direction
Pierre Procoudine-Gorsky
Visual Effects Producer
Chevin Shafaghi
Visual Effects Supervisor

Serafin Bernfeld
Special Effects Technician
Arthur Weiser
Special Effects Technician