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The Substance

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Calorie Rating: 198
Released: 2024-09-07
MPAA Rating: R
Running Time: 141 Minutes
Budget: 17500000
Revenue 76506196
Homepage: https://mubi.com/en/thesubstance
Studios: Working Title Films, Blacksmith, Working Title Films,


A fading celebrity decides to use a black market drug, a cell-replicating substance that temporarily creates a younger, better version of herself.

Director / Directors

Anne Juin
Third Assistant Director
Matthieu de la Mortière
First Assistant Director

Louis Tellier
Third Assistant Director
Clément Audebrand
Third Assistant Director
Mateo Cejoco
Third Assistant Director

Benoit Seiller
Second Assistant Director
Marianne Huet
Script Supervisor


Cast

Demi Moore
Character: Elisabeth
Margaret Qualley
Character: Sue
Dennis Quaid
Character: Harvey

Edward Hamilton-Clark
Character: Fred
Gore Abrams
Character: Oliver
Oscar Lesage
Character: Troy

Christian Erickson
Character: Man at Diner
Robin Greer
Character: Male Nurse
Tom Morton
Character: Doctor

Hugo Diego Garcia
Character: Diego - Boyfriend
Daniel Knight
Character: Casting Director
Jonathon Carley
Character: Assistant Casting Director

Jiselle Henderkott
Character: Girl Auditioning / New Year's Eve Show Dancer
Akil Wingate
Character: TV Host
Vincent Colombe
Character: Man in Suit #1 - Harvey's Office

Billy Bentley
Character: Man in Suit #2
Lennard Ridsdale
Character: Man in Suit #3
Jordan Ford Silver
Character: Assistant Director - Pump It Up Show

Oscar Salem
Character: 2nd Assistant Director - Pump It Up Show
Viviane Bossina
Character: Sue's Assistant
Matthew Luret
Character: Floor Runner

Jana Bittnerová
Character: Maria
Olivier Raynal
Character: Alan - 2nd Agent
Tiffany Hofstetter
Character: Stylist

Nicolas Royer
Character: Guy in the Elevator
Nathan Rippy
Character: Assistant Director - New Year's Eve Show
Manon Arizmendi
Character: Little Girl - New Year's Eve Show

Virginie Kotlinski
Character: Mother - New Year's Eve Show
Brett Gillen
Character: Director of Photography - New Year's Eve Show
Charlotte Marquardt
Character: Screaming Woman

Léa Hengl
Character: Screaming Woman
Gaëlle Raymond
Character: Screaming Woman
Claire Lemaire
Character: Screaming Woman

Lila Boughoufala
Character: Screaming Woman
Aurélien Lorgnier
Character: Screaming Man
Ivan Sellier
Character: Screaming Man

Philip Schurer
Character: Screaming Man
Christian Bourmier
Character: Shareholder
Martin Graham
Character: Shareholder

Christian Bordeleau
Character: Shareholder
Patrick Hamel
Character: Shareholder
Didier Dhondt
Character: Shareholder

Jacques-Yves Dorges
Character: Shareholder
Jean-Claude Matthey
Character: Shareholder
Olivier Jarcin
Character: Shareholder

Jean-Luc Magneron
Character: Shareholder
Charlotte Murray
Character: Allison - Diner Waitress
Aaron Kahn
Character: Greeting Person

Gabriela Arnon
Character: Greeting Person
Nancy Josephson Lahoussine
Character: Greeting Person
Andrew Eldridge
Character: Greeting Person

Denise Powers
Character: Greeting Person
Bryan Jones
Character: Greeting Person
Adam Carage
Character: Happy Birthday Person

Maria McClurg
Character: Happy Birthday Person
Andrew Desmond
Character: Happy Birthday Person
Rebecca Lafont
Character: Happy Birthday Person

Laura Puech
Character: Isabella
Ryan Chidester
Character: Stagehand
Céline Vogt
Character: Elisabeth (Young) - Walk of Fame

Yannick Guérin
Character: Clumsy Burger Guy - Walk of Fame
Jean Miel
Character: Worker Walk of Fame
Paul Descoings
Character: Worker Walk of Fame

Benoit Lévêque
Character: Worker Walk of Fame
Arthur Molinet
Character: Cocktail Bartender
Manon Sachot
Character: Cocktail Lounge Couple

Bastien Jorelle
Character: Cocktail Lounge Couple
Kelly Hoarau
Character: Female Assistant - Towel
Michel Juskiewicz
Character: George - Harvey's Friend

Louise Greggory
Character: Restaurant Waitress
Christophe Sartirano
Character: Guy Looking at Sue
Florent Torres
Character: Guy Looking at Sue

Romain Caldeira
Character: Billboard Technician
Barthelemy Thomas
Character: Billboard Technician
Axel Baille
Character: Photographer

Ashley Lambert
Character: Additional Voices (voice)
Ranjani Brow
Character: Additional Voices (voice)
Chase Fein
Character: Additional Voices (voice)

Shane Sweet
Character: Additional Voices (voice)
William Calvert
Character: Additional Voices (voice)
Michael Corbett
Character: Additional Voices (voice)

Stephen Apostolina
Character: Additional Voices (voice)
Yann Bean
Character: The Substance (voice)
Audjyan Alcide
Character: Pump It Up Show Dancer

Jonathan Jenvrin
Character: Pump It Up Show Dancer
Mimi Maury
Character: Pump It Up Show Dancer
Amelye Solange
Character: Pump It Up Show Dancer

Kévin Table
Character: Pump It Up Show Dancer
Laura Boera
Character: Sparkle Your Life Show Dancer
Cissy Duc
Character: Sparkle Your Life Show Dancer

Sophie Mercier
Character: Sparkle Your Life Show Dancer
Marie Valton
Character: Sparkle Your Life Show Dancer
Katrina Budzynski
Character: New Year's Eve Show Dancer

Alicia Maury
Character: New Year's Eve Show Dancer
Megane Adamik
Character: New Year's Eve Show Dancer
Annalisa Pagnotta
Character: New Year's Eve Show Dancer

Maelle Dantigny
Character: New Year's Eve Show Dancer
Aleksandra Fontaine Kedzierska
Character: New Year's Eve Show Dancer
Pauline Sagetat
Character: New Year's Eve Show Dancer

Agustina Fitzsimons
Character: New Year's Eve Show Dancer
Elena Shcheglova
Character: New Year's Eve Show Dancer
Eve Marchant
Character: New Year's Eve Show Dancer

Lola Donati
Character: New Year's Eve Show Dancer
Kate Matthews
Character: New Year's Eve Show Dancer
Ophélie Jonard
Character: New Year's Eve Show Dancer

Pauline Richard
Character: New Year's Eve Show Dancer
Laureen Cappelliez
Character: New Year's Eve Show Dancer
Daria Panchenko
Character: New Year's Eve Show Dancer

Delphine Beaulieu
Character: New Year's Eve Show Dancer
Victoria Brun
Character: New Year's Eve Show Dancer
Cara Chapman
Character: New Year's Eve Show Dancer

Katharine Matthews
Character: New Year's Eve Show Dancer
Alexandra Faget
Character: New Year's Eve Show Dancer
Clémence Juville
Character: New Year's Eve Show Dancer

Margot L'Entete
Character: New Year's Eve Show Dancer
Hillary Sukhonos
Character: New Year's Eve Show Dancer
Matthew Géczy
Character: Bob Haswell (uncredited)

Namory Bakayoko
Character: Silhouette (uncredited)
Gregory Defleur
Character: Happy Birthday Person (uncredited)
Coralie Fargeat
Character: (uncredited)


Production and Crew

Erik Baiers
Executive Producer
Stanislas Reydellet
Production Design
Frédérique Arguello
Hair Department Head

Marie Bouvet
Stunt Double
Jérôme Gaspard
Stunt Coordinator
Richard Martin
Prosthetics Sculptor

Cécilia Blom
Set Decoration
Denise Boccacci
Prosthetic Makeup Artist
Bryan Jones
Visual Effects Supervisor

Frédéric Balmer
Special Effects Makeup Artist
Andrea Leanza
Prosthetics Sculptor
Benjamin Kračun
Director of Photography

Sebastian Lochmann
Concept Artist
Krystell Morantin
Assistant Art Director

Laure Caniaux
First Assistant Camera

Vianne Burquier
Camera Intern
Steve de Rocco
Camera Operator
Thomas Gros
Key Grip

Nadege Marti
Location Scout

Chloè Acher
Second Assistant Camera
Olivier Maurin
Electrician

Charles Droudun
Electrician
Stella Libert
First Assistant Camera

Ludovic Tobaldi
Steadicam Operator
Noémie Lance
Location Manager

Catherine Georges
Camera Operator
Jonas Poignant
Third Assistant Camera

Camille Damag
Costume Supervisor
Joffrey Darel
Stunt Driver

Marie-Sophie Daniel
First Assistant Camera
Fabienne Menguy
Costume Supervisor

Nahi Margot
Electrician
Katia Sourzac
Location Production Assistant

Tanguy Goasguen
Additional Grip

Gustin Guillaume
First Assistant Camera
Olivier Sargatal
Best Boy Electric

Benjamin Colleye
Additional First Assistant Camera
Yann Festinger
Video Assist Operator
Benjamin Durfort
Assistant Editor

Baptiste Herment
Production Accountant
Baptiste Marnière
Digital Imaging Technician

Christine Tamalet
Still Photographer

Tim Bevan
Producer
Alexandra Loewy
Executive Producer
Nicolas Royer
Executive Producer

Raffertie
Original Music Composer
Oriane Cattiaux
Makeup Artist
Marison De
Special Effects Makeup Artist

Sandrine Denis
Special Effects Makeup Artist
Honorine Sutter
Assistant Production Manager
Jean Miel
Special Effects Supervisor

Benjamin Celliez
Unit Production Manager
Abraham Goldblat
Post Production Supervisor

Brian Kinney
Special Effects Makeup Artist
Julia Besnier
Production Accountant
Stéphanie Guillon
Key Makeup Artist

Pierre-Yves Frohard
Production Coordinator

Amélie Meseguer
Assistant Set Decoration
Mélissa Jacob
Additional Hairstylist
Louis Lion
Digital Compositor

Olivier Afonso
Special Effects Makeup Artist
Lucky Nguyen
Makeup Artist
Cynthia Scigliuto
Makeup Artist

Téo L'Huillier
Digital Compositor
Dave Elsey
Prosthetic Supervisor

Louis Celnik
Carpenter
Lou Elsey
Prosthetic Supervisor
Bryony Rumble
Special Effects Makeup Artist

Tiva Nagchin
Post Production Supervisor
Marion Didier
Assistant Art Director
Guillaume Le Gouez
Visual Effects Supervisor

Christophe Arnaud
Additional Second Assistant Camera
Isalys Gillet
Location Assistant
Elsa Rolland
Assistant Property Master

Elsa Manunta
Set Costumer
Olaf Taittinger
Special Effects
Louis Auger
Digital Compositor

Chloé Zobel
Property Master
Jacob Rogers
Digital Compositor

Jimmy Zhao
First Assistant Editor
Guillaume Baurez
Music Supervisor
Marjane Texier
Graphic Designer

Thomas Burgess
Steadicam Operator
Christophe Riso
Assistant Location Manager
Guillaume Billy
Camera Trainee

Raphaëlle Beck
Extras Casting
Steve Sebir
Assistant Location Manager
Aurélie Boutet
Casting Assistant

Pierre-Olivier Persin
Makeup Effects Designer

Stéphane Bécimol
Art Direction
Emmanuelle Youchnovski
Costume Designer

Victor Praud
Sound Re-Recording Mixer
Valérie Deloof
Sound Designer
Judah Getz
ADR Mixer

Olga Pasternak
Supervising Dialogue Editor

Thomas Pichon
Dialogue Editor
Stéphane Thiébaut
Sound Re-Recording Mixer

Margaux Peyre
Boom Operator
Grégory Vincent
Foley Artist

Claire Bernengo
Boom Operator
Valérie Deloof
Sound Editor
Victor Fleurant
Sound Editor

Lucien Richardson
Supervising Dialogue Editor

Amélie Meseguer
Art Direction
Arnaud Denis
Art Direction
Gladys Garot
Art Direction

Julie Plumelle
Art Direction
Nathalie Vaïsse
Art Direction
Pierre Procoudine-Gorsky
Visual Effects Producer

Chevin Shafaghi
Visual Effects Supervisor
Serafin Bernfeld
Special Effects Technician
Arthur Weiser
Special Effects Technician

Marilyne Scarselli
Key Hair Stylist
Jean-Marc Benois
Additional Hairstylist

Frédérique Arguello
Key Hair Stylist