Graduated in direction from Centro Sperimentale di Cinematografia of Rome and in Modern and Contemporary Italian Literature, he's a total artist: poet, documentary filmmaker, photographer and visual artist, writer of books on film language and theory. He taught Film at University, Screenwriting at Rai-Italian Radio and Television. He works in collaboration with his wife Mariella Buscemi, screenwriter and author. In recognition of his contribution to the arts the Calcografia Nazionale of Rome with the Ministero Beni Culturali has dedicated to the solo exhibition "Arcangelo Mazzoleni: Il Mondo al fuoco dello Sguardo. Films, Videos, Photos, Drawings and Mixed Media on paper".

Filmography